Trospium-d8 (chloride) is the deuterium-labeled form of Trospium chloride. Trospium chloride is an orally active, specific, and competitive antagonist of muscarinic cholinergic receptors (mAChRs), exhibiting antimuscarinic activity. It binds with high affinity to muscarinic receptors M1, M2, and M3, but not nicotinic cholinergic receptors.
- Used as a tracer
- Used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Incorporation of stable heavy isotopes can affect pharmacokinetic and metabolic profiles of drugs